Selected publications

Researchers using data from the Nurses' Health Studies are highly productive and generate a large volume of publications. In addition, the Nurses' Health Studies are active participants in many consortia and other collaborative research projects. Below are selected recent publications from the Studies. View selected earlier publications using the links to the left.


Farvid, Maryam S.; Tamimi, Rulla M.; Poole, Elizabeth M.; Chen, Wendy Y.; Rosner, Bernard A.; Willet, Walter C.; Holmes, Michelle D.; Eliassen, Heather A. Postdiagnostic dietary glycemic index, glycemic load, dietary insulin index, and insulin load and breast cancer survival. Caner Epidemiol. Biomarkers Rev. 2021. Available from:

Väyrynen, Juha P.; Haruki, Koichiro; Lau, Mai Chan; Väyrynen, Sara A.; Zhong, Rong; Dias Costa, Andressa; Borowsky, Jennifer; Zhao, Melissa; Fujiyoshi, Kenji; Arima, Kota; Twombly, Tyler S.; Kishikawa, Junko; Gu, Simeng; Aminmozaffari, Saina; Shi, Shanshan; Baba, Yoshifumi; Akimoto, Naohiko; Ugai, Tomotaka; Da Silva, Annacarolina; Guerriero, Jennifer L.; Song, Mingyang; Wu, Kana; Chan, Andrew T.; Nishihara, Reiko; Fuchs, Charles S.; Meyerhardt, Jeffrey A.; Giannakis, Marios; Ogino, Shuji; Nowak, Jonathan A. The prognostic role of macrophage polarization in the colorectal cancer microenvironment. Cancer Immunol Res. 2021. Available from:


He, Xiaosheng; Hang, Dong; Wu, Kana; Nayor, Jennifer; Drew, David A.; Giovannucci, Edward L.; Ogino, Shuji; Chan, Andrew T.; Song, Mingyang. Long-term tisk of colorectal cancer after removal of conventional adenomas and serrated polyps. Gastroenterology. 2020. Available from:

Li, Yanping; Schoufour, Josje; Wang, Dong D.; Dhana, Klodian; Pan, An; Liu, Xiaoran; Song, Mingyang; Liu, Gang; Shin, Hyun Joon; Sun, Qi; Al-Shaar, Laila; Wang, Molin; Rimm, Eric B.; Hertzmark, Ellen; Stampfer, Meir J.; Willett, Walter C.; Franco, Oscar H.; Hu, Frank B. Healthy lifestyle and life expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study. BMJ. 2020. Available from:

Guasch-Ferre, Marta; Liu, Gang; Li, Yanping; Sampson, Laura; Manson, Joann E.; Salas-Salvado, Jordi; Martinez-Gonzalez, Miguel A.; Stampfer, Meir J.; Willett, Walter C.; Sun, Qi; Hu, Frank B. Olive oil consumption and cardiovascular risk in US adults. Journal of the American College of Cardiology. 2020. Available from:

Drouin-Chartier, Jean-Philippe; Chen, Siyu; Li, Yanping; Schwab, Amanda L.; Stampfer, Meir J.; Sacks, Frank M.; Rosner, Bernard; Willett, Walter C.; Hu, Frank B.; Bhupathiraju, Shilpa N. Egg consumption and risk of cardiovascular disease: three large prospective US cohort studies, systematic review, and updated meta-analysis. BMJ. 2020. Available from:

O'Brien, Katie M.; Tworoger, Shelley S.; Harris, Holly R.; Anderson, Garnet L.; Weinberg, Clarice R.; Trabert, Britton; Kaunitz, Andrew M.; D'Aloisio, Aimee A.; Sandler, Dale P.; Wentzensen, Nicolas. Association of powder use in the genital area with risk of ovarian cancer. JAMA. 2020. Available from:

Michaud, Dominique S.; Ruan, Mengyuan; Koestler, Devin C.; Pei, Dong; Marsit, Carmen J.; De Vivo, Immaculata; Kelsey, Karl T. Epigenome-wide association study using prediagnostic bloods identifies new genomic regions associated with pancreatic cancer risk. JNCI Cancer Spectr. 2020. Available from:

Farvid, Maryam S.; Holmes, Michelle D.; Chen, Wendy Y.; Rosner, Bernard A.; Tamimi, Rulla M.; Willet, Walter C.; Eliassen, Heather A. Postdiagnostic fruit and vegetable consumption and breast cancer survival: Prospective analyses in the Nurses’ Health Studies. Cancer Res. 2020. Available from:

Zheng, Xiaobin; Hur, Jinhee; Nguyen, Long H.; Liu, Jie; Song, Mingyang; Wu, Kana; Smith-Warner, Stephanie A.; Ogino, Shuji; Willet, Walter C.; Chan, Andrew T.; Giovannucci, Edward; Cao, Yin. Comprehensive assessment of diet quality and risk of precursors of early-onset colorectal cancer. J Natl Cancer Inst. 2020. Available from:


Liu, Po-Hong; Wu, Kana; Ng, Kimmie; Zauber, Ann G.; Nguyen, Long H.; Song, Mingyang; He, Xiaosheng; Fuchs, Charles S.; Ogino, Shuji; Willett, Walter C.; Chan, Andrew T.; Giovannucci, Edward L.; Cao, Yin. Association of obesity with risk of early-onset colorectal cancer among women. JAMA Oncology. 2019. Available from:

Malik, Vasanti S.; Li, Yanping; Pan, An; De Koning, Lawrence; Schernhammer, Eva; Willett, Walter C.; Hu, Frank B. Long-term consumption of sugar-sweetened and artificially sweetened beverages and risk of mortality in US adults. Circulation. 2019. Available from:

Zheng, Yan; Li, Yanping; Satija, Ambika; Pan, An; Sotos-Prieto, Mercedes; Rimm, Eric; Willett, Walter C.; Hu, Frank B. Association of changes in red meat consumption with total and cause specific mortality among US women and men: two prospective cohort studies. BMJ. 2019. Available from:

Farvid, Maryam S.; Chen, Wendy Y.; Rosner, Bernard A.; Tamimi, Rulla M.; Willett, Walter C.; Eliassen, A. Heather. Fruit and vegetable consumption and breast cancer incidence: Repeated measures over 30 years of follow-up. International Journal of Cancer. 2019. Available from:

Banay, Rachel F.; James, Peter; Hart, Jaime E.; Kubzansky, Laura D.; Spiegelman, Donna; Okereke, Olivia L.; Spengler, John D.; Laden, Francine. Greenness and depression incidence among older women. Environmental Health Perspectives. 2019. Available from:


Li, Yanping; Pan, An; Wang, Dong D.; Liu, Xiaoran; Dhana, Klodian; Franco, Oscar H.; Kaptoge, Stephen; Di Angelantonio, Emanuele; Stampfer, Meir; Willett, Walter C.; Hu, Frank B. Impact of Healthy Lifestyle Factors on Life Expectancies in the US Population. Circulation. 2018. Available from:

Eckel N, Li Y, Kuxhaus O, Stefan N, Hu FB, Schulze MB. Transition from metabolic healthy to unhealthy phenotypes and association with cardiovascular disease risk across BMI categories in 90 257 women (the Nurses' Health Study): 30 year follow-up from a prospective cohort study. Lancet Diabetes Endocrinol. 2018. Available from:

Simon, Tracey G.; Ma, Yanan; Ludvigsson, Jonas F.; Chong, Dawn Q.; Giovannucci, Edward L.; Fuchs, Charles S.; Meyerhardt, Jeffrey A.; Corey, Kathleen E.; Chung, Raymond T.; Zhang, Xuehong; Chan, Andrew T. Association Between Aspirin Use and Risk of Hepatocellular Carcinoma. JAMA Oncology. 2018. Available from:

Cao, Yin; Wu, Kana; Mehta, Raaj; Drew, David A.; Song, Mingyang; Lochhead, Paul; Nguyen, Long H.; Izard, Jacques; Fuchs, Charles S.; Garrett, Wendy S.; Huttenhower, Curtis; Ogino, Shuji; Giovannucci, Edward L.; Chan, Andrew T. Long-term use of antibiotics and risk of colorectal adenoma. Gut. 2018. Available from:

Song, Mingyang; Wu, Kana; Meyerhardt, Jeffrey A.; Ogino, Shuji; Wang, Molin; Fuchs, Charles S.; Giovannucci, Edward L.; Chan, Andrew T. Fiber intake and survival after colorectal cancer diagnosis. JAMA Oncology. 2018. Available from: https:/


Kim ES, Hagan KA, Grodstein F, DeMeo DL, De Vivo I, Kubzansky LD. Optimism and Cause-Specific Mortality: A Prospective Cohort Study. Am J Epidemiol. 2017;185(1):21-29. PMC5209589. Available from:

Lebwohl B, Cao Y, Zong G, Hu FB, Green PHR, Neugut AI, et al. Long term gluten consumption in adults without celiac disease and risk of coronary heart disease: prospective cohort study. BMJ. 2017;357:j1892. PMC5421459.  Available from:

Mehta RS, Nishihara R, Cao Y, Song M, Mima K, Qian ZR, et al. Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue. JAMA Oncol. 2017;3(7):921-927. PMC5502000. Available from:

Yu E, Ley SH, Manson JE, Willett W, Satija A, Hu FB, et al. Weight History and All-Cause and Cause-Specific Mortality in Three Prospective Cohort Studies. Ann Intern Med. 2017;166(9):613-620. PMC5518318. Available from:

Zheng Y, Manson JE, Yuan C, Liang MH, Grodstein F, Stampfer MJ, et al. Associations of Weight Gain From Early to Middle Adulthood With Major Health Outcomes Later in Life. JAMA. 2017;318(3):255-269. Available from:


Bertoia ML, Rimm EB, Mukamal KJ, Hu FB, Willett WC, Cassidy A. Dietary flavonoid intake and weight maintenance: three prospective cohorts of 124,086 US men and women followed for up to 24 years. BMJ. 2016;352:i17. PMC4730111. Available from:

Dehghan A, Bis JC, White CC, Smith AV, Morrison AC, Cupples LA, et al. Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. PLoS One. 2016;11(3):e0144997. PMC4780701. Available from:

Liu Y, Tobias DK, Sturgeon KM, Rosner B, Malik V, Cespedes E, et al. Physical activity from menarche to first pregnancy and risk of breast cancer. Int J Cancer. 2016;139(6):1223-1230. PMC5257171. Available from:

Mu F, Rich-Edwards J, Rimm EB, Spiegelman D, Missmer SA. Endometriosis and Risk of Coronary Heart Disease. Circ Cardiovasc Qual Outcomes. 2016;9(3):257-264. PMC4940126. Available from:

Sisti JS, Collins LC, Beck AH, Tamimi RM, Rosner BA, Eliassen AH. Reproductive risk factors in relation to molecular subtypes of breast cancer: Results from the nurses' health studies. Int J Cancer. 2016;138(10):2346-2356. PMC5245093. Available from:

Sotos-Prieto M, Mattei J, Hu FB, Chomistek AK, Rimm EB, Willett WC, et al. Association Between a Healthy Heart Score and the Development of Clinical Cardiovascular Risk Factors Among Women: Potential Role for Primordial Prevention. Circ Cardiovasc Qual Outcomes. 2016;9(2 Suppl 1):S77-85. PMC4772164. Available from:

Vetter C, Devore EE, Wegrzyn LR, Massa J, Speizer FE, Kawachi I, et al. Association Between Rotating Night Shift Work and Risk of Coronary Heart Disease Among Women. JAMA. 2016;315(16):1726-1734. PMC5102147. Available from:

Yuan C, Clish CB, Wu C, Mayers JR, Kraft P, Townsend MK, et al. Circulating Metabolites and Survival Among Patients With Pancreatic Cancer. J Natl Cancer Inst. 2016;108(6):djv409. PMC4849356. Available from:


Chomistek AK, Chiuve SE, Eliassen AH, Mukamal KJ, Willett WC, Rimm EB. Healthy lifestyle in the primordial prevention of cardiovascular disease among young women. J Am Coll Cardiol. 2015;65(1):43-51. PMC4291551. Available from:

Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, et al. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat Genet. 2015;47(11):1294-1303. PMC4661791. Available from:

Huang T, Poole EM, Okereke OI, Kubzansky LD, Eliassen AH, Sood AK, et al. Depression and risk of epithelial ovarian cancer: Results from two large prospective cohort studies. Gynecol Oncol. 2015;139(3):481-486. PMC4679423. Available from: